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Little did the people of Jacksonville, Florida, know that they were running from mosquitoes!

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U.S. Army Physicians Discovered the Cause of Yellow Fever
August 27, 1900
Prior to this experiment, epidemics of yellow fever were common in the American South. Not knowing how the disease was transmitted, many people would leave the South for the summer, when epidemics were most common. In an 1888 yellow fever epidemic in Jacksonville, Florida, terrified citizens packed themselves onto trains leaving town. Some were so panicked, they left fires burning and the doors of their houses wide open. The Mayflower Hotel, where the epidemic started, was condemned and ordered burned to the ground.
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